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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1984 Nov;36(6):1386–1393.

A method of processing first-trimester chorionic villous biopsies for cytogenetic analysis.

K J Blakemore, M S Watson, J Samuelson, W R Breg, M J Mahoney
PMCID: PMC1684634  PMID: 6517058

Abstract

Chorionic villous biopsy is emerging as a technique for obtaining fetal cells for prenatal diagnosis in the first trimester of pregnancy. Chromosome analysis has been performed on small villous biopsies using either direct harvests of uncultured cells or after culturing villous tissue. Here, we describe a method where both techniques can be used simultaneously; from a single villous biopsy, GTG-banded chromosomes of improved morphology are obtained from direct preparations and from cultured villous cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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