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. 2000 Aug 1;97(16):9221–9225. doi: 10.1073/pnas.97.16.9221

Figure 3.

Figure 3

Dosage effect of intratumorally injected adenoviral vectors on the growth of a human melanoma tumor in SCID mice. The mice were first injected s.c. with the human melanoma cell line LXSN, and when a skin tumor had grown to the size indicated on day 0 the tumor was injected with a mixture of the two adenoviral vectors encoding the mfVIIasm and G71-1 immunoconjugates. The dose for the two vectors was as follows. ○, 6 × 109 IU; ▵, 2 × 109 IU; □, 7 × 108 IU. The dose for the control vector that did not encode an immunoconjugate was as follows. ⋄, 6 × 109 IU.