Figure 6.

Image quality of microPET I. (A) Two 1.5-mm-thick longitudinal whole body sections of a 25-g mouse using [F-18]fluoride ion to image skeletal system of prostate cancer mouse model with bone metastases (arrows). (B) Longitudinal whole body FDG images of glucose metabolism in normal 250-g rat. (C Upper) Cross sections through chest of rat showing glucose metabolism in left (arrow) and right ventricles. Left ventricle is 9 mm in diameter, with 1-mm wall thickness. Right ventricle is thinner, and metabolic rate is 1/3 left. (Lower) Coronal sections of glucose metabolism in rat brain weighing 1 g, showing cortex well separated from internal structure of striatum. (D) Images of mouse brain with [C-11]WIN 35,428 that binds to dopamine reuptake transporters showing clear separation of left and right striatum (arrow) that each weigh about 12 mg. (E) FDG brain images of two-month-old Vervet monkey with good delineation of cortical and subcortical structures. Dimension across brain is 2 cm. Cortical convolutions of brain are not seen because the young monkey has few of them. Reprinted with permission from ref. 31.