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Sequence alignment between gp42 and the NK domains of two Ly49 family members. The N-terminal amino acids containing cytoplasmic and transmembrane portions of each protein are omitted. The strictly conserved cysteine residues are denoted by framed boxes. * represent Ly49A amino acids that are involved in cis binding based on the crystal structure of Ly49A complexed with MHC class I. + depicts Ly49A amino acids that comprise the trans-binding domain.
