Table 7.
Comparison of defects in central location of study eye at baseline visit with defects at randomization visit, in late entry patients, with correction for short term fluctuation (SFC)
| Defect at randomization visit (RV)* | ||||||||
| Paracentral | Central | Neither paracentral nor central | Total | |||||
| Defect at baseline visit | No. (%) | % at RV | No. (%) | % at RV | No. (%) | % at RV | No. (%) | % at RV |
| Paracentral | 2 (28.6) | 0 | 5 (71.4) | 13.9 | 0 | 0 | 7 (100.0) | 14.9 |
| Central | 0 | 0 | 17 (94.4)† | 47.2 | 1 (5.6) | 11.1 | 18 (100.0) | 38.3 |
| Neither paracentral nor central | 0 | 0 | 14 (63.6) | 38.9 | 8 (36.4) | 88.9 | 22 (100.0) | 46.8 |
| Total | 2 (4.3) | 100.0 | 36 (76.6) | 100.0 | 9 (19.2) | 100.0 | 47 (100.0) | 100.0 |
* p = 0.0003; Stuart Maxwell test for marginal homogeneity
† p = 0.09 for change in severity, 11.5 dB at baseline versus 6.7 dB at randomization; paired t test