Figure 5.

Reduction of LTD, but not LTP, in spinophilin knockout mice. (a) LTD in wild-type and knockout mice after low-frequency stimulation. (b) Representative traces for recordings before (Pre) and 45 min after (Post) low-frequency stimulation. (Bars = 1 mV, 10 msec.) (c) LTP in wild-type and knockout mice in response to high-frequency stimulation. Double triangles indicate two tetanic stimulations (100 Hz for 1 sec each, with a 20-sec interval). (d) Representative traces for recordings before (Pre) and 45 min after (Post) high-frequency tetanic stimulation. (Bars = 1 mV, 10 msec.)