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. 2006 Nov 28;4:7. doi: 10.1186/1476-8518-4-7

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Copyright © 2006 Huang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Correlation between VL and HIV-specific responses. A significant reduction of 0.44 log₁₀unit occurred from TI#1 VL plateau to TI#2 VL plateau (p = 0.004) and decreased 0.48 log10 units from TI#1 VL plateau to TI#3 VL plateau (p = 0.055). Despite this, no correlation was evident between VL improvement and either the increase in the magnitude or the breadth of HIV-specific immune response; VL improvement is the difference between the TI#1 and TI#2 VL plateau; increase in the magnitude is the difference in SFCs between TI#1 and TI#2; increase in breadth is the difference in the number of epitopes recognized between TI#1 and TI#2.