Table 5.

Combined effect of MMP1 and MMP3.1 loci in small adenomas

Genotypes		Polyp free (n)	Small adenoma (n)	OR* (95% CI)
MMP1	MMP3.1
1G-1G	5A-5A	76	47	1
1G-1G	5A-6A	58	26	0.77 (0.41–1.43)
1G-1G	6A-6A	19	5	0.37 (0.12–1.12)
1G-2G	5A-5A	46	18	0.68 (0.34–1.38)
1G-2G	5A-6A	174	88	0.83 (0.52–1.33)
1G-2G	6A-6A	56	33	1.13 (0.62–2.04)
2G-2G	5A-5A	8	3	0.63 (0.15–2.62)
2G-2G	5A-6A	59	18	0.45 (0.23–0.89)
2G-2G	6A-6A	51	55	1.88 (1.08–3.28)

* OR adjusted on age, sex and group of centres