Figure 4.

Laminar shear stress causes a decrease in the percentage of phosphorylated Rb in BAECs. Confluent BAECs were subjected to laminar shear stress at 12 dynes/cm² for periods of time as indicated, or kept as static control represented by time 0. The amounts of hypo- and hyperphosphorylated Rb were determined by densitometry. “Rb-P” represents the hyperphosphroylated Rb and “Total Rb” is the sum of Rb-P and hypophosphorylated Rb. The bars represent the mean ± SD from three experiments. * denotes P < 0.05 compared with the static controls.