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. 2000 Aug 1;97(17):9455–9460. doi: 10.1073/pnas.160175897

Figure 5.

Figure 5

Schematic drawing of the hydration of the planar p-quinone methide intermediate of 4-ethylphenol in D170S/T457E. We propose that the Glu-457-activated water attacks the quinone methide, yielding the (S)-enantiomer of the alcohol.