Table 2. Current list of motifs included in Scansite.
Phosphoserine/threonine binding domains | 14-3-3 mode 1 |
Tyrosine kinase domains | Abl |
EGFR | |
FGFR | |
Insulin receptor | |
Itk | |
Lck | |
PDGFR | |
Src | |
Src homology 2 domains | Abl |
Crk | |
FGFR | |
Fyn | |
Grb2 | |
Itk | |
Lck | |
Nck | |
p85 | |
PLC γ (C terminal SH2) | |
PLC γ (N terminal SH2) | |
Shc | |
SHIP | |
Src | |
Src homology 3 domains | Abl |
Amphiphysin | |
Cbl-associated protein | |
Cortactin | |
Crk | |
Grb2 | |
Intersectin | |
Itk | |
Nck | |
p85 α (mode 1) | |
p85 α (mode 2) | |
PLC γ | |
Src | |
Basophilic serine/threonine kinase domains | Akt |
Calmodulin-dependent kinase 2 | |
Clk2 | |
Protein kinase A | |
PKC α/β/γ | |
PKC δ | |
PKC ɛ | |
PKC μ | |
PKC ζ | |
DNA damage kinase domains | ATM |
DNA protein kinase | |
Acidophilic serine/threonine kinase domains | Casein kinase 1 |
Casein kinase 2 | |
GSK3 | |
Proline-dependent serine/threonine kinase domains | Cdc2 |
Cdk5 | |
Erk1 | |
p38 MAP kinase | |
Kinase binding domains | Erk1 |
PDK1 | |
PDZ binding domains | PDZ class 1 |
PDZ class 2 | |
PDZ (nNOS) class 1 | |
PDZ (nNOS) class 3 | |
Phosphotyrosine binding domains | Shc |
Lipid binding domains | PIP3-binding PH |