Figure 1.

Onto-Tools (clockwise, from top left): regulated genes are analyzed with Onto-Express to find significantly impacted biological processes. Specific hypotheses can be formulated based on such processes. Onto-Compare can be used to select those commercial microarrays that cover best the hypothesized mechanism. If no satisfactory array is available, Onto-Design can be used to design a custom array for that specific set of hypotheses. Onto-Translate may be used at any time to translate between UniGene cluster IDs, accession numbers and array specific Affymetrix identifiers.