Fig. 8. Lung bacteriology. Healthy CBA/J mice (10 in each group) were infected with PAO1 as described in the text. Furanone C-30 (solid bars; concentration as indicated below the x-axis) or saline (open bars) were given three times a day (every 7 h) for 3 days. The mice were killed on day 7 after the bacterial challenge and the bacterial content of the infected lungs was determined as described in the text. Average values were plotted and the standard deviation is shown by error bars. The values were tested by means of an F-test (analysis of variance), and the p values for the 0.7, 0.4 and the 0.2 µM C-30 concentrations were 0.0007, 0.004 and 0.5, respectively.