Table 1.
Histology of the hind feet in acute bovine CIA
| Arthritic changes | Intraperitoneal, n = 20/group
|
Oral, n = 12/group
|
|||
|---|---|---|---|---|---|
| Control | CBD, 5 mg/kg | Control | CBD, 25 mg/kg | CBD, 50 mg/kg | |
| Normal | 0% | 34%* | 0% | 0% | 0% |
| Mild | 31% | 26% | 20% | 41% | 34% |
| Moderate | 31% | 20% | 5% | 34% | 16% |
| Severe | 38% | 20% | 75% | 25%** | 50% |
Histological findings at the end of the experiments in classical CIA. The results are shown as the percentage of all feet studied that were given a specified score. *, P = 0.0083; **, P = 0.0373 (Fisher's exact test).