Table 5.
LPS-induced rise in serum TNF is blocked by simultaneous administration of CBD
Control, LPS | CBD i.p. | CBD s.c. | |
---|---|---|---|
Serum TNF (S50) | 3,572 ± 892 | 679 ± 321 | 377 ± 85 |
Mice were injected with LPS, 100 μg, i.p. CBD was administered simultaneously, either i.p. or s.c. Mice were bled 90 min later, and TNF was measured by bioassay. Results are the mean ± SD of n = 13 per group.