Table 1.

Ten most common somatic alterations in BRCAX cancers (percentage of cases), as compared to other hereditary and unselected breast cancers by CGH

Location	BRCAX	BRCA1 (7)	BRCA2 (7)	Unselected (10)
Loss 13q21–q31	56	55	73*	26
Gain 1q22–q32	46	55	53	66
Loss 6q16–q24	41	27	60	18
Gain 17q23	39	46	87	18
Gain 8q23–q24	36	73	53	49
Gain 16p13–p12	34	27	40	38
Loss 11q14–q24	30	23	53	18
Gain 19q	30	18	40	20
Loss 9p23–p21	26	27	40	20
Loss Xq	26	40	47	20

^*Target area 13cen–q21.