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Lethality of the P. aeruginosa ppk mutant in a burned-mouse model
| Strain | Relevant genotype | Mortality, mice dead/total*
|
|||
|---|---|---|---|---|---|
| Exp. 1 | Exp. 2 | Exp. 3 | Average, % | ||
| PAO1 | WT | 7/7 | 5/6 | 6/6 | 94 |
| PAOM5 | Δppk∷TcR | 1/5 | 0/5 | 0/5 | 7 |
| PAOM5 (pHEPAK11) | Δppk∷TcR (PPK+++) | 2/5 | 3/5 | 3/5 | 53 |
Burned-mice were inoculated s.c. with ≈200 cells of each strain; mortality was checked after 48 h. Exp., experiment.
