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Effect of bradykinin on arterial blood pressure in anesthetized mice. (A) Original tracing showing the effect of a bolus application of bradykinin (Bk; 10 μg/kg, i.v.) on blood pressure (BP) in a diclofenac- (10 mg/kg, i.p.) and l-NAME- (30 mg/kg, i.p.) treated mouse. (B and C) Effect of bolus application of saline or bradykinin (doses indicated above the bars) on MAP in the absence (B) or in the presence (C) of diclofenac and l-NAME; n ≥ 5 each group; ∗, P < 0.05.
