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The ability of NE (0.1–1.0 μg/kg), given as bolus i.v injections to an anesthetized rat, to increase MAP (■) is prevented after incubation with HX/XO (⧫). This ability is protected by the inclusion of M40403 in the incubate (▵; n = 6). Incubation period was 5 min for each experiment.
