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. 2006 Nov 21;103(49):18597–18602. doi: 10.1073/pnas.0609061103

Fig. 4.

Fig. 4.

Interdependence of NHEJ protein assembly on DSBs. (A and B) Accumulation of Ku80 (green) in XRCC4-deficient XR-1 cells (A) and in DNA-PKCS mutant XR-C1 cells (B). (C and D) Accumulation of XRCC4 protein in XR-V15B cells expressing EGFP-Ku80 (C) and in DNA-PKCS-deficient XR-C1 cells (D). The arrowheads in C point to cells that do not express EGFP-Ku80. (Scale bars: 5 μm in A, B, and D and 20 μm in C.)