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. 2006 Nov 22;103(49):18715–18720. doi: 10.1073/pnas.0604800103

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© 2006 by The National Academy of Sciences of the USA

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Fig. 2. — PML influences IFN-γ-regulated genes. (A) RNA from immortalized Pml^+/+ and Pml^−/− MEF untreated or treated with IFN-γ for 4 h was subjected to microarray analysis. The proportion of genes that are up- or down-regulated (2-fold change) between untreated and IFN-γ-treated cells is shown. (B) RNA from immortalized Pml^+/+ and Pml^−/− MEF treated with IFN-γ for the indicated times was subjected to RPA for IP-10 and GAPDH mRNA levels. Fold induction is shown. Representative of three independent experiments.