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. 2006 Nov 9;103(47):17718–17723. doi: 10.1073/pnas.0608556103

Fig. 2.

Fig. 2.

Morphology of testes from 14-wk-old AR+/y, PM-AR−/y, and AR−/y male mice. (A and B) Decreased testes size in PM-AR−/y mice. PM-AR−/y mice have genitourinary organs of similar size as AR+/y mice except for smaller testes, which were 76% of T-AR−/y mice (n= 10; ∗, P < 0.05 vs. AR+/y). In contrast, there are small testes but no seminal vesicle, epididymis, or prostate in T-AR−/y mice. Arrows indicate testes (each unit of the rule equals 1 mm). (C–E) Serum testosterone, LH, and FSH levels in 14-wk-old male AR+/y, PM-AR−/y, and T-AR−/y mice (n= 8, 8, and 5, respectively). PM-AR−/y mice have normal range of serum testosterone, LH, and FSH levels compared with AR+/y mice; in contrast, T-AR−/y mice have significantly lower serum testosterone and higher LH and only a marginal change in FSH level compared with the age-matched AR+/y and PM-AR−/y mice (∗, P < 0.05 vs. AR+/y).