Table 1.

Some de novo/ab initio servers for protein folding

Sl. No.	Name of the Web Server/Group	Description
1.	ROBETTA (28,29) (http://robetta.bakerlab.org)	De novo Automated structure prediction analysis tool used to infer protein structural information from protein sequence data
2.	PROTINFO (30) (http://protinfo.compbio.washington.edu)	De novo protein structure prediction web server utilizing simulated annealing for generation and different scoring functions for selection of final five conformers
3.	SCRATCH (31) (http://www.igb.uci.edu/servers/psss.html)	Protein structure and structural features prediction server which utilizes recursive neural networks, evolutionary information, fragment libraries and energy
4.	ASTRO-FOLD (32)	Astro-fold: first principles tertiary structure prediction based on overall deterministic framework coupled with mixed integer optimization
5.	ROKKY (33) (http://www.proteinsilico.org/rokky/rokky-p/)	De novo structure prediction by the simfold energy function with the multi-canonical ensemble fragment assembly
6.	BHAGEERATH (http://www.scfbio-iitd.res.in/bhageerath)	Energy based methodology for narrowing down the search space of small globular proteins