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. Author manuscript; available in PMC: 2006 Dec 11.
Published in final edited form as: FEBS Lett. 2006 Sep 22;580(24):5733–5738. doi: 10.1016/j.febslet.2006.09.027

Figure 1.

Figure 1

Amino acid sequences and transmembrane topology of the α1 subunit of voltage-gated Ca2+ channels. (A) Amino acid sequences of the S6 segments in the four repeats of Cav2.1 subunit and the S6 segment in the third repeat of Cav2.2 and Cav1.2 subunit. I1520 in Cav2.1 and homologous residues in Cav2.2 and Cav1.2 are shown in italics. (B) Putative transmembrane topology of the α1 subunit of voltage-gated Ca2+ channels. The black dot at the intracellular end of IIIS6 shows the location of I1520.