TABLE 1.

Activities of daptomycin and vancomycin against a collection of S. aureus strains with various vancomycin susceptibilities

Phenotype	No. of strains	Antimicrobial agent	Range of MICs	MIC50	MIC90	% Susceptible	% Resistant	Geometric mean MIC
GSSA/MSSA	11	Vancomycin	1-2	1	2	100	0	1.1
		Daptomycin	0.25-0.5	0.25	0.5	100	0	0.3
GSSA/MRSA	95	Vancomycin	0.5-2	1	2	100	0	1.2
		Daptomycin	0.12-1	0.25	0.5	100	0	0.3
hGISA	55	Vancomycin	1-4	2	4	100	0	2.4
		Daptomycin	0.12-2	0.5	1	98.2	1.8	0.5
GISA	15	Vancomycin	4-8	4	8	60	40	5.5
		Daptomycin	0.5-2	1	2	86.7	13.3	0.9