FIG. 4.

Effects of LPV/r and ATV on body and tissue weights. Ten-week-old mice were treated daily for 8 weeks with the LPV/r at 200/50 mg/kg/day or ATV at 90 mg/kg/day or received the control treatment (Con). (A) Mice were analyzed for their body weights; and their inguinal WAT (WAT ing), epididymal WAT (WAT epi), and BAT depots were dissected and weighed. Values are normalized to 1 for control animals ± the standard error of the mean. Inguinal WAT was significantly affected by the LPV/r treatment (P = 0.0004). (B) Representative histological analysis of inguinal WAT depots of either control or LPV/r-treated mice. D, dermis; F, fibrous trabecula. Magnification, ×10.