FIG. 8.

Cartoon illustrating proposed evolutionary history of glycolytic enzymes within the excavates. The arrows show gain or replacement of enzymes, and crosses represent enzyme loss after the split from the last common excavate ancestor. Kinetoplastids are proposed to have diverged first, followed by the oxymonads, with parabasalids and diplomonads diverging last. The various events are most parsimoniously interpreted as evidence consistent with the proposed relationships shown.