TABLE 3.

Marginal logistic regression models of the effects of reinfection with Schistosoma japonicum on the odds of anemia in 580 7- to 30-year-old patients^a

Variable	All-cause anemiab			Iron-deficiency anemiab			Non-iron-deficiency anemiab
	β	SE	P value	β	SE	P value	β	SE	P value
Interceptc	−0.287	0.095	0.0024	−0.635	0.102	<0.0001	−1.431	0.135	<0.0001
T3	0	0		0	0		0	0
T6	−0.430	0.094	<0.0001	−0.385	0.092	<0.0001	−0.429	0.146	0.003
T9	−0.201	0.127	0.11	−0.219	0.142	0.12	−0.184	0.17	0.28
T12	−0.699	0.144	<0.0001	−0.618	0.154	<0.0001	−0.685	0.194	<0.001
T15	−0.915	0.18	<0.0001	−0.934	0.193	<0.0001	−0.851	0.245	<0.001
T18	−0.670	0.200	<0.001	−0.591	0.223	0.008	−0.668	0.253	0.008
Aged	−0.091	0.014	<0.0001	−0.103	0.017	<0.0001	−0.077	0.017	<0.0001
Sexd	0.063	0.156	0.68	−0.048	0.187	0.80	0.125	0.181	0.49
Socioeconomic statusd	−0.278	0.083	<0.001	−0.368	0.102	<0.001	−0.168	0.099	0.091
Hookworm egg counte	0.001	0.016	0.97	0.008	0.019	0.68	−0.024	0.021	0.26
Baseline S. japonicum egg countd	0.082	0.051	0.11	0.099	0.059	0.094	0.067	0.058	0.25
Durationf	−0.012	0.023	0.59	−0.054	0.025	0.032	0.052	0.021	0.012
S. japonicum egg countg	0.017	0.033	0.61	−0.014	0.034	0.69	0.109	0.039	0.005
Duration × S. japonicum egg counth	0.014	0.005	0.003	0.018	0.005	<0.0001

^aβ-estimates (excluding the intercept) represent changes in log odds of the outcome per unit change of the exposure. β-Estimates and SE were adjusted for within-person associations and for confounding by covariates. T3 to T18 represent the trimonthly posttreatment follow-ups, and the 3-month follow-up is the reference category.

^bAll-cause anemia is defined as a hemoglobin level below the WHO cutoff. Iron-deficiency anemia is defined as a hemoglobin level below the WHO cutoff and an SF level of ≤30 ng/ml. Non-iron-deficiency anemia is defined as a hemoglobin level below the WHO cutoff and an SF level of >30 ng/ml.

^cThe intercept represents the log odds of the outcome at the 3-month follow-up for an average individual (i.e., an individual with a mean value for each of the covariates). The P value indicates whether the intercept is significantly different from zero.

^dThe confounders age, sex, socioeconomic status, and baseline ln-transformed S. japonicum egg count were centered on the baseline means.

^eln-transformed hookworm egg counts were centered on the mean of all posttreatment observations.

^fDefined as the time since reinfection with S. japonicum.

^gln-transformed S. japonicum egg count.

^hInteraction term.