TABLE 2.
The dbpBA locus is not required for infection of immunodeficient micea
Inoculum | Plasmids missing | No. of cultures positive/total no. of specimens examined
|
|||
---|---|---|---|---|---|
Heart | Joint | Skin | All sites | ||
5A18NP1 | lp28-4, lp56, lp5 | 5/5 | 5/5 | 5/5 | 15/15 |
dbpAB/01 | cp9, lp28-4, lp56, lp5 | 2/2 | 2/2 | 2/2 | 6/6 |
dbpAB/02 | cp9, lp28-4, lp56, lp5 | 2/2 | 2/2 | 2/2 | 6/6 |
dbpAB/03 | cp9, lp28-4, lp56, lp21, lp5 | 2/2 | 2/2 | 2/2 | 6/6 |
Each of the three dbpAB clones was inoculated into two SCID mice, and the parental clone 5A18NP1 was inoculated into five mice as a control. All animals were sacrificed 1 month after inoculation. Heart, tibiotarsal joint, and skin specimens were harvested and cultured for spirochetes in BSK-H complete medium.