Mean serum (a) TNF-α, (b) cortisol, (c) SAA, and (d) haptoglobin concentrations in transgenic (⋄) and control (▪) cows after an intramammary infusion of 1,700 CFU of E. coli into a single udder quarter during the experiment. Data are presented as means ± SEM for six transgenic and five control cows. The P values indicated in panel b are 0.003 (*), 0.031 (**), and 0.048 (***) for cortisol, and those in panel d are 0.035 (*) and 0.029 (**) for serum haptoglobin.