Table 1.
Baseline characteristics of study participants, Kindamba, ROC 2004
| AS + AQ | AS + SP | Coartem | Total | P-value | |
|
Number of patients (% of total) |
101 (33.9) | 91 (30.5) | 106 (35.6) | 298 | |
| Sex: F/M (% F) | 46/55 (45.5) | 38/53 (41.8) | 50/56 (47.2) | 134/164 (45.0) | P = 0.74 |
| Age* (months) | 20.5 ± 10.7 (7–48) | 23.0 ± 11.9 (6–54) | 36.1 ± 11.1 (12–59) | 26.8 ± 13.2 (12–59) | P < 0.00 1 |
| Weight*(Kg) | 9.7 ± 2.3 (6–16) | 10.1 ± 2.4 (5–19) | 12.7 ± 2.0 (10–20) | 10.9 ± 2.6 (5–20) | P < 0.00 1 |
| MUAC* (mm) | 142.5 ± 13.8 (112–180) | 143.5 ± 11.8 (100–188) | 151.5 ± 10.6 (130–190) | 146.1 ± 12.7 (100–190) | P < 0.00 1 |
|
Haemoglobin* (g/dl) |
8.8 ± 1.7 (5.0–12.8) | 9.1 ± 1.7 (5.1–12.3) | 9.6 ± 1.7 (5.1–14.2) | 9.2 ± 1.7 (5.0–14.2) | P = 0.00 3 |
|
Moderate anaemia ‡ (Hgb 5 < 8 g/dl) |
30 (29.7) | 25 (27.5) | 16 (15.2) | 71 (23.9) | P = 0.03 |
|
Mild anaemia ‡ (Hgb 8 < 11 g/dl) |
59 (58.4) | 53 (58.2) | 66 (62.9) | 178 (59.9) | P = 0.80 |
| Temperature *(°C) | 38.0 ± 1.2 (35.8–40.0) | 37.8 ± 1.3 (34.8–40.7) | 37.9 ± 1.3 (34.8–40.7) | 37.9 ± 1.3 (34.8–40.7) | P = 0.32 0 |
|
Parasite density** (per μl) |
28,941 (2040–200,000) | 24,997 (1200–200,000) | 23,997 (2000–200,000) | 25,890 (1200–200,000) | P = 0.65 1 |
| Gametocytes ‡ | 23 (22.8) | 24 (26.4) | 9 (8.5) | 56 (18.8) | P = 0.00 3 |
* Values given as mean ± SD (Standard Deviation) and range (min-max value),
** Parasite density given as geometric mean and range.
‡ Anaemia/gametocytemia described by number + proportion of cases with anaemia/gametocytes.