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. 2006 Oct 6;92(1):76–86. doi: 10.1529/biophysj.106.088757

FIGURE 6.

FIGURE 6

Single-channel currents in the presence of 20 mM choline of single- and double-mutant AChRs. (Left) Channel traces corresponding to wild-type, single- (αM1-F15′L or αM2-L11′F), and double-mutant (αM1-F15′L+αM2-L11′F) AChRs. Clusters are shown at two different timescales. Membrane potential: −70 mV. Openings are shown as upward deflections at a bandwidth of 5 kHz. Right: Open- and closed-time histograms with the fit to the Scheme 1 superimposed to the experimental histograms. Ordinates correspond to the square root of the fraction of events per bin.