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Molecular modeling of AChRs carrying mutations at αM2-11′ and αM1-15′. The refined coordinates of Torpedo AChR (PDB with accession code 2BG9) (37) were used. Molecular surface of part of αM1 and αM2 and the residues of interest as sticks are shown. (A) Wild-type AChR, (B) αM1-F15′L, (C) αM2-L11′F, and (D) αM1-F15′L+αM2-L11′F.
