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Graphical representation of our hypothetical model illustrating the potential links between NikR and the different NikR-regulated genes in nickel uptake and nickel utilization in H. pylori. The outer membrane (OM), cytoplasmic membrane (CM), periplasm (PP), and cytoplasm (CY) are indicated. Gray arrows represent genes involved in nickel utilization, black arrows represent genes involved in nickel transport, and white arrows represent genes involved in regulation of transcription.
