TABLE 1.
Expression of CXCR3 ligands during S. enterica serovar Enteritidis infection
| Infection type and chemokine | Mean chemokine concn ± SEMa in:
|
|||
|---|---|---|---|---|
| Spleen (ng/ml)
|
Liver (pg/ml)
|
|||
| Control | Serovar Enteritidis | Control | Serovar Enteritidis | |
| Primary infection | ||||
| CXCL9 | 2.5 ± 0.2 | 9.8 ± 0.2† | 11.2 ± 0.4 | 39.6 ± 1.9† |
| CXCL10 | 0.23 ± 0.04 | 0.26 ± 0.03 | 5.1 ± 1.8 | 4.2 ± 0.8 |
| CXCL11 | 0.95 ± 0.24 | 0.79 ± 0.09 | 14.2 ± 2.7 | 13.4 ± 2.3 |
| Secondary infection | ||||
| CXCL9 | 4.2 ± 0.3 | 5.6 ± 0.4* | 14.2 ± 2.5 | 31.0 ± 3.4* |
| CXCL10 | 0.21 ± 0.01 | 0.24 ± 0.05 | 7.5 ± 1.4 | 8.1 ± 0.9 |
| CXCL11 | 0.67 ± 0.05 | 0.67 ± 0.04 | 18.9 ± 4.1 | 17.9 ± 1.7 |
a
Chemokine concentrations are expressed as ng/ml and pg/mg tissue at day 5 after infection for the spleen and liver, respectively (n = 14 to 16). *, P < 0.01; †, P < 0.001 (versus control).