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Protection of mice immunized with the triple-chimeric B subunit ABC against a lethal challenge of Stx1 or Stx2
| Group | Immunization with ABC | Challenge with 10 LD50s ofa: | No. of surviving mice/total no. of mice |
|---|---|---|---|
| 1 | − | Stx1 | 0/7 |
| 2 | + | Stx1 | 6/7 |
| 3 | − | Stx2 | 0/7 |
| 4 | + | Stx2 | 1/6 |
The LD50s were previously determined to be 125 and 1 ng/mouse for Stx1 and Stx2, respectively. The average weight of the mice at the time of the challenge was 44.9 g.
