TABLE 3.
l-Lysine formation with C. glutamicum strain DM1730 as a function of the substrates glucose and myo-inositol and mixtures of these substrates
| Timea | Glucose concn (mM) | Inositol concn (mM) | Growth (OD) | l-Lysineb concn (mM) | Yieldc (mol/mol) |
|---|---|---|---|---|---|
| I | 202.0 | 0 | 14 | 37.8 | 0.19 |
| I | 186.8 | 16.6 | 24 | 40.5 | 0.20 |
| I | 176.7 | 27.7 | 23 | 38.1 | 0.19 |
| I | 0 | 222.0 | 17 | 23.0 | 0.10 |
| II | 202.0 | 0 | 21 | 63.6 | 0.31 |
| II | 186.8 | 16.6 | 23 | 44.1 | 0.22 |
| II | 176.7 | 27.7 | 24 | 38.3 | 0.19 |
| II | 0 | 222.0 | 19 | 22.7 | 0.10 |
a
Time I gives growth, l-lysine concentration, and yield after 24 h, whereas time II gives the values after 48 h, when all of the sugar was consumed.
b
All data are mean values of at least three independent cultivations with errors of <5% for l-lysine concentrations and yields.
c
Molar yields are given as moles of l-lysine per mole of carbon source consumed.