TABLE 4.
Cationic agent (concn [μg/ml]) | % Survival
|
Survival ratio (WT/ΔnodPQ mutant) | % Survival of ΔcysH mutant | Survival ratio (WT/ΔcysH mutant) | |
---|---|---|---|---|---|
Wild type | ΔnodPQ mutant | ||||
Polymyxin B (20) | 99.6 | 112.7 | 88.4 | 100.3 | 99.3 |
Poly-l-lysine (50) | 73.6 | 103.2 | 71.3 | 96.5 | 76.3 |
Cationic peptide killing assays were performed with polymyxin B and poly-l-lysine. Results were recorded as percent survival after a 1-h exposure to the cationic peptide at the concentration indicated. The results shown are the average of three experiments. WT, wild type.