TABLE 1.
Immunolabeling in postsynaptic targets
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Acb region | Terminal labeling | Synaptic subtype | None | D2 | CB1 | D2/CB1 |
Shell | CB1 | Excitatory | 44.8 | 20.7 | 6.9 | 0.0 |
N = 87* | Inhibitory | 13.8 | 2.3 | 4.6 | 6.9 | |
Core | CB1 | Excitatory | 42.7 | 20.6 | 3.7 | 2.4 |
N = 82 | Inhibitory | 17.1 | 4.9 | 4.9 | 3.7 | |
Shell | D2 | Excitatory | 56.5 | 8.7 | 4.3 | 0.0 |
N = 42 | Inhibitory | 19.6 | 0.0 | 8.7 | 2.2 | |
Core | D2 | Excitatory | 30.6 | 11.1 | 8.3 | 5.6 |
N = 36 | Inhibitory | 19.4 | 5.6 | 13.8 | 5.6 |
Number of synaptic CB1 or D2 labeled terminals in an area of approximately 10,000 μm2 in each Acb region from two sections in four rats. Tissue was processed using immunogold for CB1 and immunoperoxidase for D2 receptors.