TABLE 2.
Intraspecies hypervariable regions in 35 C. jejuni strains
| Region | Start-end in RM1221 (NCTC 11168) | Function and/or gene(s) | No. of strains possessing region similar to:
|
No. of strains divergent from both | |
|---|---|---|---|---|---|
| RM1221 | NCTC 11168 | ||||
| 1 | CJE0031-CJE0035 (Cj0032-Cj0036)b | Type IIS restriction/modification | NAd | NA | 16 |
| 2 | CJE0051-CJE0055 (Cj0055c-Cj0059c)a | Unknown | 11 | 11 | 13 |
| 3 | CJE0170-CJE0175 (Cj0177-Cj0182)b | Putative iron transport, biopolymer transport, tonB, exbB1, exbD1 | NA | NA | 14 |
| 17 | CJE0308-CJE0313 (Cj0258-Cj0263)c | pyrC, putative zinc transport | 5 | 19 | 11 |
| 4 | CJE0340-CJE0355 (Cj0294-Cj0310c)c | Pantothenate and biotin biosynthesis pathway | 3 | 14 | 18 |
| Molybdenum ABC transporter | |||||
| 5 | CJE0470-CJE0472 (Cj0421c-Cj0425)a | Unknown | 10 | 16 | 9 |
| 6 | CJE0530-CJE0538 (Cj0480c-Cj0490)b | Unknown, uxaA | NA | NA | 24 |
| 7 | CJE0666-CJE0673 (Cj0561c-Cj0571)a | Unknown | 5 | 14 | 16 |
| 8 | CJE0728-CJE0732 (Cj0625-Cj0629)a | Hydrogenase, hypA, hypD, hypE | 3 | 17 | 15 |
| Type III restriction/modification (CJE0731-CJE0732) | |||||
| 9 | CJE0828-CJE0844 (Cj0727-Cj0755)b | Phosphate-regulated genes (Cj0727-Cj0733) (25) | NA | NA | 11 |
| Iron uptake (Cj0752-Cj0755), tonB3, cfrA | |||||
| 18 | CJE0944-CJE0947 (Cj0857c-Cj0860)b | Unknown | NA | NA | 22 |
| 10 | CJE1047-CJE1056 (Cj0967-Cj0975)a | Unknown | 4 | 17 | 14 |
| 11 | CJE1278-CJE1281 (Cj1135-Cj1145c)a | LOS | 3 | 3 | 29 |
| 12 | CJE1485-CJE1532 (Cj1293-Cj1343)a | FM, O-linked glycosylation locus | 1 | 5 | 29 |
| 13 | CJE1601-CJE1622 (Cj1414c-Cj1449c)a | CAP | 3 | 3 | 29 |
| 14 | CJE1714-CJE1733 (Cj1543c-Cj1563c)a | RM, type I restriction/modification and unknown | 3 | 5 | 27 |
| 15 | (Cj1677-Cj1679)a | Unknown | 21 | 8 | 6 |
| 16 | CJE1888-CJE1896 (Cj1717c-Cj1729c)a | leuA, leuB, leuC, and unknown | 5 | 2 | 28 |
a
NCTC 11168 and RM1221 are highly divergent.
b
NCTC 11168 and RM1221 are not distinguished by microarray, only the number of isolates divergent from both are reported.
c
NCTC 11168 and RM1221 are highly divergent; however, RM1221 genes are absent from the microarray. Isolates with the same presence/absence pattern as RM1221 for these regions were scored as possessing the RM1221 region.
d
NA, not applicable, since NCTC 11168 and RM1221 are not distinguished by microarray.