TABLE 2.

Determination of heterogeneity of VNTR at each MIRU locus of M. bovis clinical isolates

No. of TR copiesa	No. of isolates at VNTR-MIRU locus
	2	4	10	16	20	23	24	26	27	31	39	40
0
1
2	42		42	1	42		42		30	2	42	41
2′		6
3		33		40					12	37		1
3′		3
4				1		42		1		2
5								41		1
6
7
8
Allelic diversityb	0.00	0.34	0.00	0.07	0.00	0.00	0.00	0.02	0.39	0.20	0.00	0.02

^aTR, tandem repeat. The symbol ′ indicates alleles devoid of 53-bp sequences at the 3′ terminus of the MIRU locus.

^bAllelic diversity (h) was calculated using the equation h = 1 − Σ x_i² [n/(n − 1)], where n is the number of isolates and x_i the frequency of the ith allele at the locus (23).