TABLE 1.
MIC ranges, MIC50s, and MIC90s of AMN and comparator agents for Candida spp.
| Candida sp.a | AMN
|
AMB
|
VOR
|
CAS
|
MFN
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | |
| C. parapsilosis | 0.03-2.0 | 1.0/2.0 | 0.25-0.5 | 0.25/0.5 | <0.016-0.12 | <0.016/0.03 | 0.12-1.0 | 0.5/1.0 | 0.12-8.0 | 4.0/8.0 |
| C. krusei | 0.03-4.0 | 0.12/0.5 | 0.25-2.0 | 0.5/1.0 | <0.016-0.25 | 0.12/0.25 | 0.25-16 | 0.5/1.0 | 0.016-64 | 0.25/2.0 |
| C. guilliermondii | 0.12-1.0 | 0.5/1.0 | 0.12-1.0 | 0.25/0.5 | <0.016-0.25 | 0.03/0.06 | 0.25-2.0 | 0.5/1.0 | 0.12-4.0 | 2.0/2.0 |
| C. tropicalis | 0.06-2.0 | 0.25/1.0 | 0.25-4.0 | 1.0/1.0 | <0.016-32 | <0.016/0.06 | 0.06-8.0 | 0.25/1.0 | 0.001-8.0 | 0.06.0.5 |
| All yeasts | 0.03-4.0 | 0.5/1.0 | 0.12-4.0 | 0.5/1.0 | <0.016-32 | 0.03/0.12 | 0.06-16 | 0.5/1.0 | 0.001-64 | 0.5/8.0 |
a
Twenty-five isolates of each species were tested.