TABLE 2.
MIC ranges, MIC50s, and MIC90s of AMN and comparator agents against filamentous fungi
| Isolatea | AMN
|
AMB
|
VOR
|
CAS
|
MFN
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | MIC50/MIC90 (μg/ml) | |
| A. fumigatus | 0.12-0.5 | 0.25/0.5 | 0.5-1.0 | 0.5/1.0 | 0.06-0.5 | 0.12/0.25 | 0.5 | 0.5/0.5 | 0.016-0.06 | 0.03/0.06 |
| Fusarium | 128->256 | >256/>256 | 1.0-4.0 | 1.0/4.0 | 1.0-4.0 | 2.0/4.0 | 64-256 | 128/256 | >256 | >256/>256 |
| Scedosporium | 4.0-8.0 | 8.0/8.0 | 1.0-8.0 | 4.0/4.0 | 0.25-8.0 | 4.0/4.0 | 1.0-16 | 16/16 | 2.0->256 | 64/>256 |
| Zygomycetes | 4.0->16 | 16/>16 | 0.06-1.0 | 0.25/0.5 | 2.0->8.0 | 4.0/>8.0 | 4.0->16 | >16/>16 | 1.0->256 | >256/>256 |
a
Twenty-five isolates of each species were tested.