TABLE 1.
Characteristics and antibiotic resistance profiles of MRSA strains recovered from adults at Vanderbilt University Medical Center, 15 November 2004 to 14 November 2005
| Variable | No. (%) of SCCmec-II strains (n = 398) | No. (%) of SCCmec-IV strains (n = 423) | P |
|---|---|---|---|
| Isolation site | |||
| Bloodstream | 83 (20.9) | 31 (7.3) | <0.000001 |
| Respiratory | 151 (37.9) | 28 (6.6) | <0.000001 |
| Skin, soft tissue, abscess, and post surgical wounds | 127 (31.9) | 352 (83.2) | <0.000001 |
| Others | 37 (9.3) | 12 (2.8) | <0.0001 |
| Antibiotic resistance | |||
| Methicillin, penicillin, amoxicillin | 398 (100.0) | 423 (100.0) | NSa |
| Clavulanate, cefazolin | |||
| Erythromycin | 393 (98.7) | 381 (90.1) | <0.000001 |
| Clindamycinb | 386 (97.0) | 56 (13.2) | <0.000001 |
| Gentamicin | 29 (7.3) | 4 (0.9) | <0.00001 |
| Levofloxacin | 386 (97.0) | 70 (16.8) | <0.000001 |
| Minocycline | 3 (0.8) | 0 (0.0) | NS |
| Rifampin | 17 (4.3) | 0 (0.0) | <0.0001 |
| Trimethoprim-sulfamethoxazole | 9 (2.3) | 8 (1.9) | NS |
| Vancomycin | 0 (0.0) | 0 (0.0) | NS |
| PVL gene occurrence | 0 (0.0) | 377 (89.1) | <0.000001 |
a
NS, not significant.
b
Includes inducible resistance.