TABLE 2.
Characteristics and antibiotic resistance profiles of MRSA strains recovered from children at Vanderbilt University Medical Center, 15 November 2004 to 14 November 2005
| Variable | No. (%) of SCCmec-II strains (n = 50) | No. (%) of SCCmec-IV strains (n = 424) | P |
|---|---|---|---|
| Isolation site | |||
| Bloodstream | 6 (12.0) | 9 (2.1) | <0.001 |
| Respiratory | 31 (62.0) | 18 (4.2) | <0.000001 |
| Skin, soft tissue, abscess, and post surgical wounds | 12 (24.0) | 390 (92.0) | <0.000001 |
| Others | 1 (2.0) | 7 (1.7) | NSa |
| Antibiotic resistance | |||
| Methicillin, penicillin, amoxicillin-clavulanate, cefazolin | 50 (100.0) | 424 (100.0) | NS |
| Erythromycin | 47 (94.0) | 387 (91.3) | NS |
| Clindamycinb | 43 (86.0) | 34 (8.0) | <0.000001 |
| Gentamicin | 0 (0.0) | 1 (0.2) | NS |
| Levofloxacin | 39 (78.0) | 18 (4.2) | <0.000001 |
| Minocycline | 0 (0.0) | 0 (0.0) | NS |
| Rifampin | 0 (0.0) | 1 (0.2) | NS |
| Trimethoprim-sulfamethoxazole | 0 (0.0) | 1 (0.2) | NS |
| Vancomycin | 0 (0.0) | 0 (0.0) | NS |
| PVL gene occurrence | 1 (2.0) | 416 (98.1) | <0.000001 |
a
NS, not significant.
b
Includes inducible resistance.