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. 2006 Nov 30;7(1):138. doi: 10.1186/1465-9921-7-138

Table 3.

Progression with age of lung function within genetic groups stratified according frequency of CFTR mutations.

A Progression with age of lung function B Comparison of progression between genetic groups C Comparison of progressions within groups in relation to ΔF508(2) * D delta of Power analysis 0.8
Slopes within groups Intercept at age 6 to 8 yrs mean comparison Slope differences (age range 6 to 18 yrs)

F-value sign. F-value sign. mean diff. sign.

FRCpleth ΔF508(2) 0.151 1.117 n.s. 3.979 0.008
3905insT/ΔF 0.215 1.057 0.048 0.09154
R553X/ΔF 0.165 0.120 n.s. 0.09969
LCI ΔF508(2) 0.247 5.077 0.002 0.491 n.s.
3905insT/ΔF 0.291 1.865 0.006 0.200854
R553X/ΔF 0.278 0.307 n.s. 0.236018
VTG ΔF508(2) 0.198 3.372 0.019 6.499 0.0001
3905insT/ΔF 0.233 1.036 0.011 0.113801
R553X/ΔF 0.256 0.065 n.s. 0.128347
sReff ΔF508(2) 0.405 0.849 n.s. 10.043 0.0001
3905insT/ΔF 0.549 1.297 n.s. 0.305402
R553X/ΔF 0.741 3.298 0.039 0.328812
FEV1 ΔF508(2) -0.185 4.542 0.004 13.066 0.0001
3905insT/ΔF -0.216 2.502 0.009 0.16809
R553X/ΔF -0.466 0.431 n.s. 0.18238
FEF50 ΔF508(2) -0.439 1.774 n.s. 14.255 0.0001
3905insT/ΔF -0.738 1.011 n.s. 0.30235
R553X/ΔF -1.029 2.952 0.002 0.32759
Misc -0.354

* adjusted for multiple comisons according Bonferroni