Skip to main content
. Author manuscript; available in PMC: 2006 Dec 13.
Published in final edited form as: Development. 2005 Aug 3;132(17):3873–3883. doi: 10.1242/dev.01946

Fig. 7.

Fig. 7

Rescue of cell migration defects in Psen1-/- embryos with a nestin-Psen1 transgene. Pregnant females were given one dose of BrdU at E12.5 and the embryos were collected at E18.5 and immunostained with anti-BrdU antibodies. Shown are BrdU-immunostained sections through the lateral cerebral wall of E18.5 embryos from wild-type (A), Psen1+/- (B), Psen1-/- (C), nestin-Psen1 transgene on Psen1-/- background (D) and nestin-Psen1 transgene on Psen1+/+ background (E). BrdU labeling is dispersed in the Psen1-/- embryo and normalized by the nestin-Psen1 transgene. Cortical layers (MZ, CP, SP, IZ, VZ) are indicated as in Fig. 5. Scale bar: 100 μm.