TABLE 3.

Genes and operons in gram-positive bacteria^a containing functional cre's or being regulated by the P-Ser-HPr:CcpA complex

Organism	Gene/operon	Function	cre sequenceb	CcpA effectc	Reference(s)
B. megaterium	bamM	β-Amylase	+48TGTTAACGCTTTCA+61	−	457
B. megaterium	mbgA	β-Galactosidase	−34TGATAAGGTTTTCA−21	−	803
B. megaterium	mbgA	β-Galactosidase	−21AGAAAACGTTATCA−8	−	803
B. megaterium	xyl	Xylose metabolism	+124TGAAAGCGCAAACA+137	−	290
B. thuringiensis	cry4A	Cry4A toxin	NI	−	399
C. perfringens	cpe	Enterotoxin	NI	+	913
C. saccharobutylicum	staA	Starch degradation	NI	−	162
E. faecalis	bkd	β-Keto acid metabolism	NI	−	933
E. faecalis	galKETR	Galactose metabolism	NI	−	453
E. faecalis	gdh dhaK	Glycerol dehydrogenase/dihydroxyacetone kinase	NI	−	453
E. faecalis	?	Glucose starvation-induced proteins	NI	−	453
E. faecalis	ldh	Lactate dehydrogenase	NI	−	453
E. faecalis	pfk	Phosphofructo kinase	NI	−	453
E. faecalis	pyk	Pyruvate kinase	NI	−	453
E. faecalis	?	Serine dehydratase	NI	−	453
L. casei	nag	N-Acetylglucosaminidase	NI	−	568, 796
L. casei	lac	Lactose metabolism	NI	−	568
L. delbrueckii subsp. bulgaricus	ccpA	Catabolism repression	NI	−	574
L. delbrueckii subsp. lactis	pepQ	Peptidase	−61TGCAATCGCTTACA−48	+	799
L. lactis	las	Glycolysis	NI	+	494
L. lactis	gal	Galactose metabolism	NI	−	494
L. lactis	ptbA bglH	β-Glucoside metabolism	NI	−	569
L. lactis	fruRCA	Fructose metabolism	NI	−	45
L. monocytogenes	?	β-Glucosidase	NI	−	50
L. pentosus	xpkA	Xylulose-5-P phosphoketolase	NI	−	674
L. pentosus	xylAB	Xylose metabolism	NI	−	489
L. plantarum	bglH	P-β-glucosidase	−3TGTAAGGGCTATCA+11	−	511, 512
S. aureus	pckA	PEP carboxy kinase	NI	−	791
S. bovis	ccpA	CcpA	−68TGAAAAGGTTTTCA-54	+	27
S. bovis	ldh	Lactate dehydrogenase	NI	−	27
S. bovis	pfl	Pyruvate formate lyase	NI	+	27
S. gordonii	abpA	Amylase binding	NI	−	733
S. gordonii	arcA	Arginine deiminase	NI	−	195
S. mutans	fruA	Fructan hydrolase	−164AGATAGCGCTTACA−150	−	93, 946
S. mutans	ftf	Fructosyltransferase	NI	+	88
S. mutans	gtfBC	Glucosyltransferase	NI	+	88
S. pneumoniae	cps	Capsular polysaccharide	NI	+	273
S. rattus	arcA	Arginine deiminase	NI	−	298
S. thermophilus	lacSZ	Lactose metabolism	NI	−	897
S. thermophilus	ldh	Lactate dehydrogenase	NI	−	897
S. xylosus	?	β-Glucoronide	NI	−	204
S. xylosus	ccpA	Catabolic repressor	NI	−	204
S. xylosus	lacPH	Lactose metabolism	NI	−	46
S. xylosus	mal	Maltose metabolism	−58TGCAAACGCTTGCA−45	−	204
Consensus sequence			TGWNANCGNTNWCA		939

^aExcept B. subtilis (for this organism, see references 178, 575, and 980).

^bThe numbers indicate the position with respect to the transcription initiation site. NI means not experimentally identified.

^cCcpA acts either as catabolite activator (+) or as catabolite repressor (−).