FIG. 1.

Components of the archaeal DNA replication machinery and chromatin proteins. Structure figures were prepared using Pymol (www.pymol.org), using the following PDB coordinates: Pyrobaculum Cdc6, 1FNN; Sulfolobus SSB, 1O71; Pyrococcus RFC small subunit, 1IQP; Sulfolobus Pol B1, 1S5J; Pyrococcus PCNA, 1ISQ; Archaeoglobus Fen1, 1RXW; Sulfolobus Alba, 1H0Y; Sulfolobus Sul7d, 1WTP; and Methanothermus histone HmfB, 1BFM. The image of the ligase structure was supplied by Y. Ishino (Fukuoka, Japan), and we obtained the image of the primase complex in collaboration with L. Pellegrini (Cambridge, United Kingdom).