Figure 2. .
Analysis of a suite of case-control studies with disease parameters GRR(Aa)=2, GRR(AA)=3, q=0.04, and ncc=2,000, sampled from the constant population with the full ascertainment tSNP set. A, Association structure for a simulated case-control study. ▵ denotes the position of the (untyped) causative SNP. B,Probability of there being a significant association within an interval around the causative SNP. C and D, Markerwise P values at the marker closest to the causative SNP for each of the 50 studies. E, Cumulative distribution of distances between the association peak and the causative SNP. F, Distribution of estimated allele frequency.